Albores-Saavedra J, Molberg K, Henson D E
Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75235-90720, USA.
Semin Diagn Pathol. 1996 Nov;13(4):326-38.
Most malignant epithelial tumors of the gallbladder are heterogenous and classified as adenocarcinomas. The authors report a previously unrecognized group of unusual gallbladder carcinomas including two cases of signet ring cell carcinoma in situ, three of cribriform invasive adenocarcinoma, and one of adenocarcinoma with pseudoangiosarcomatous features. In addition, the authors review their material and update the information on clear cell, small cell, and undifferentiated carcinoma of the gallbladder. A new morphologic variant of undifferentiated carcinoma mimicking lobular carcinoma of the breast is identified. The clinical, morphologic, and immunohistochemical features of these unusual neoplasms are emphasized.
大多数胆囊恶性上皮性肿瘤具有异质性，归类为腺癌。作者报告了一组先前未被认识的不寻常胆囊癌，包括2例原位印戒细胞癌、3例筛状浸润性腺癌和1例具有假血管肉瘤特征的腺癌。此外，作者回顾了他们的病例资料并更新了胆囊透明细胞癌、小细胞癌和未分化癌的相关信息。发现了一种模仿乳腺小叶癌的未分化癌新形态学变体。强调了这些不寻常肿瘤的临床、形态学和免疫组化特征。
