图像-DNA细胞计量术对胃癌患者的临床重要性及预后价值
Clinical importance and prognostic value of the image-DNA-cytometry for patients with gastric cancer.
作者信息
Stratmann H, Decker D, Hirner A, Bollmann R
机构信息
Department of Surgery, Rheinische Friedrich-Wilhelms-Universität Bonn, Germany.
出版信息
Gen Diagn Pathol. 1996 Oct;142(2):97-100.
Image-DNA-cytometric analysis was performed retrospectively on air-dried touch preparations from gastric carcinoma from 122 patients who underwent surgery from 1989-1994. The results of DNA cytometry were compared with conventional histologic staging and grading. Aneuploidy could be verified in 81 cases (66.3%), and a significant correlation was demonstrated between aneuploidy and a high incidence of lymph node metastases, whereas no correlation with tumor type and histologic grade was detected. Thus DNA ploidy may by useful in predicting prognosis in gastric cancer.
对1989年至1994年期间接受手术的122例胃癌患者的空气干燥触片进行回顾性图像-DNA细胞计量分析。将DNA细胞计量分析结果与传统组织学分期和分级进行比较。在81例（66.3%）病例中可证实存在非整倍体，非整倍体与高淋巴结转移发生率之间存在显著相关性，而未检测到与肿瘤类型和组织学分级的相关性。因此，DNA倍性可能有助于预测胃癌的预后。
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