Kabe J
Yugawara Kosei-Nenkin Hospital.
Nihon Rinsho. 1996 Nov;54(11):2886-92.
Although the concept of asthma management of the Japanese Guidelines is basically similar in the other guidelines including GINA, ICR, of British Thoracic Society, and of the other countries, assuming that asthma is a chronic inflammatory disorder of the airway, the program of stepwise pharmacologic therapy is not the same in various points. Therapy suggested in the Japanese Guidelines is different in 1) oral antiallergic drugs are widely used, 2) patients prefer oral bronchodilators to inhaled bronchodilators, 3) sustained released theophylline in the long term management and intravenous infusion of aminophylline for the treatment of acute exacerbation are accepted and frequently used by the physicians. Also the differences in the choice of medication between GINA, which is characterized by concept of cost, and other guidelines are discussed.
尽管日本哮喘管理指南的概念在包括全球哮喘防治创议（GINA）、英国胸科学会的ICR以及其他国家的其他指南中基本相似，即假设哮喘是一种气道慢性炎症性疾病，但逐步药物治疗方案在多个方面并不相同。日本指南中建议的治疗方法在以下方面存在差异：1）口服抗过敏药物被广泛使用；2）患者更喜欢口服支气管扩张剂而非吸入性支气管扩张剂；3）医生接受并经常使用长效缓释茶碱进行长期管理以及静脉输注氨茶碱治疗急性加重。此外，还讨论了以成本概念为特征的GINA与其他指南在药物选择上的差异。
