Internal Medicine Department, Hospital Son Llatzer, Palma de Mallorca, Spain,
Int Urol Nephrol. 2014 Jan;46(1):243-6. doi: 10.1007/s11255-012-0361-3. Epub 2013 Jan 6.
Fibromuscular dysplasia (FMD) is a noninflammatory nonatherosclerotic vascular disease. It is the second cause of renovascular hypertension after atherosclerosis. Although FMD usually has a good prognosis, renal infarctions and artery dissections have been described. We present the case of a 38-year-old woman with hypertension and asymptomatic bilateral renal infarctions. Bilateral FMD of segmental branches of the renal arteries was diagnosed by digital subtraction angiography after an exhaustive study. Previous intake of nonsteroidal anti-inflammatory drugs may also have played a significant role in the development of renal infarctions. To our knowledge, bilateral renal infarctions complicating FMD have been reported in only four previous cases; only in one of those cases, renal infarctions were asymptomatic.
纤维肌性发育不良(FMD)是一种非炎症性、非动脉粥样硬化性血管疾病。它是继动脉粥样硬化之后引起肾血管性高血压的第二大病因。虽然 FMD 通常预后良好,但已有肾梗死和动脉夹层的相关描述。我们报告了一例 38 岁女性,患有高血压和无症状性双侧肾梗死。经过详尽的研究,数字减影血管造影诊断为双侧肾动脉节段性分支的 FMD。此前服用非甾体抗炎药也可能在肾梗死的发展中起重要作用。据我们所知,此前仅报道过 4 例并发 FMD 的双侧肾梗死病例;其中仅 1 例为无症状性肾梗死。