石鱼毒液中去甲肾上腺素及其他生物胺的存在。
Presence of norepinephrine and other biogenic amines in stonefish venom.
作者信息
Garnier P, Grosclaude J M, Goudey-Perrière F, Gervat V, Gayral P, Jacquot C, Perrière C
机构信息
Laboratoire de Biologie et Contrôle des Organismes Parasites, Université de Paris-Sud, Châtenay-Malabry, France.
出版信息
J Chromatogr B Biomed Appl. 1996 Oct 25;685(2):364-9. doi: 10.1016/s0378-4347(96)00203-4.
Although fish venoms exert a cardiovascular effect, the presence of adrenergic substances was not previously demonstrated. Chromatographic analysis with electrochemical detection showed the presence of substances co-migrating with norepinephrine, dopamine and tryptophan. Serotonin, which was thought to be implicated in the intense pain following fish envenomation, was not detected. Norepinephrine was identified as a component of the stonefish Synanceia verrucosa venom by gas chromatography-mass spectrometry.
尽管鱼毒会产生心血管效应，但之前并未证实其中存在肾上腺素能物质。采用电化学检测的色谱分析表明，存在与去甲肾上腺素、多巴胺和色氨酸共同迁移的物质。未检测到血清素，而血清素曾被认为与鱼中毒后的剧痛有关。通过气相色谱-质谱联用技术，确定去甲肾上腺素是玫瑰毒鲉毒液的一种成分。
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