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山楂新鲜植物器官及药物制剂中酚类提取物的氧物种清除活性。

Oxygen species scavenging activity of phenolic extracts from hawthorn fresh plant organs and pharmaceutical preparations.

作者信息

Bahorun T, Gressier B, Trotin F, Brunet C, Dine T, Luyckx M, Vasseur J, Cazin M, Cazin J C, Pinkas M

机构信息

Laboratoire de Pharmacognosie, Faculté des Sciences Pharmaceutiques et Biologiques, Lille, France.

出版信息

Arzneimittelforschung. 1996 Nov;46(11):1086-9.

PMID:8955870
Abstract

Different extracts of fresh vegetative and reproductive organs from Crataegus monogyna harvested during a whole season and from some pharmaceutical hawthorn preparations exhibit in vitro antioxidant activities using three different models of oxygen reactive species generation (superoxide anion, hydrogen peroxide and hypochlorous acid). All the tested samples show low IC50 values, the most efficient being fresh young leaves, fresh floral buds and pharmaceutical dried flowers. The activities seem to be especially bound to the total phenolic proanthocyanidin and flavonoid contents.

摘要

对整个季节采集的单花山楂新鲜营养器官和生殖器官的不同提取物,以及一些药用山楂制剂,使用三种不同的活性氧生成模型(超氧阴离子、过氧化氢和次氯酸)进行体外抗氧化活性测试。所有测试样品的半数抑制浓度(IC50)值都很低,其中最新鲜的幼叶、新鲜花芽和药用干花的抗氧化活性最高。这些活性似乎尤其与总酚原花青素和类黄酮含量有关。

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