Lee J S, Lee M C, Park C S, Juhng S W
Department of Pathology, Chonnam University Medical School, Kwangju, Seoul, Korea.
Acta Cytol. 1996 Nov-Dec;40(6):1309-12. doi: 10.1159/000334027.
Multinucleated giant cells of osteoclastlike appearance are seen in some anaplastic carcinomas, but only three cases in which the diagnosis was made by aspiration cytology are reported in the international medical literature.
A 66-year-old female presented with a history of a palpable neck mass. The diagnosis of fine needle aspiration cytology was anaplastic thyroid carcinoma with osteoclastlike giant cells. Immunohistochemical staining and DNA ploidy analysis were done.
Osteoclastlike giant cells have an origin different from that of the anaplastic component. DNA aneuploidy was noted in our case.
在一些间变性癌中可见破骨细胞样多核巨细胞，但国际医学文献中仅报道了3例通过细针穿刺细胞学诊断的病例。
一名66岁女性，有可触及颈部肿块病史。细针穿刺细胞学诊断为伴有破骨细胞样巨细胞的间变性甲状腺癌。进行了免疫组织化学染色和DNA倍体分析。
破骨细胞样巨细胞的起源与间变性成分不同。我们的病例中发现了DNA非整倍体。
