The danger of infections of the hospitalized patients with the microorganisms present in preparations and in the hospital environment.

Two strains-S. aureus and coagulase-negative staphylococcus, resistant to antibiotics, were isolated from previously non-opened preparations made by the hospital pharmacy and industrially produced. After application in the surgery ward, two Enterobacter agglomerans strains, resistant to antibiotics were detected in oral mixtures. The resistant bacteria, B. cereus and 4 strains of Ps. aeruginosa, were also found in the purified water. In hospital environment 9 strains of staphylococci, resistant to the tested antibiotics were found. Only one of them was S. aureus (detected on the wall), the others being coagulase-negative staphylococci. Most of them were isolated from the floor, but also from the wall, table and from the air in surgical and ophthalmological wards and in the hospital pharmacy. The most dangerous were three Gram-negative strains resistant to all tested antibiotics. They were isolated from the floor (Enterobacter cloacae), from the wall (Proteus mirabilis) and from the container with oral mixture in infant ward (Ps. malthophilia). Many strains resistant to many antibiotics were detected on the floor of surgical, nephrological and infantile wards as well as from the pharmacies: Enterobacter cloacae (7 strains), Citrobacter freundi, Ps. aeruginosa, Ps. cepacia (2 strains), Ps. maltophilia (2 strains) and Moraxella. Many resistant strains were also present on the walls (E. coli, Ps. mirabilis, Ps. cepacia, Alcaligens, Acinetobacter). The resistant strains were rarely observed on the table, medical equipment and on personnel hands. Klebsiella oxytoca and Ps. paucimobilis were found on the table, Ps. maltophilia on the dropper and on the rim of the container with oral mixture. Acinetobacter and Pseudomonas sp. were isolated from the medicine glass, Enterobacter cloacae and Pseudomonas sp. from the personnel hands in the pharmacies.