Synthesis and biological activities of some 7,8-dihydroimidazo[1,2-a]-1,3,5-triazine derivatives.
作者信息
Saczewski F, Nasal A
机构信息
Department of Organic Chemistry, Medical University of Gdańsk, Poland.
出版信息
Acta Pol Pharm. 1995 May-Jun;52(3):237-40.
PMID:8960254
Abstract
The alkylation of 7,8-dihydroimidazo[1,2-a]-1,3,5-triazine-2,4-(3H,6H)-dithione [I] with 2-chloro-N-arylacetamides gave 2-alkyltio derivatives [III]. Further reactions of 2-(alkyltio)-7,8-dihydroimidazo[1,2-a]-1,3,5-triazine-4(6H)- thiones [III] or [IV] with aryl isothiocyanates, sulfochlorides or 2-bromo-1-phenylethanone afforded corresponding B-substituted products [V,VI,VII].
摘要
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