Mackrides P S, Shaughnessy A F
Harrisburg Family Practice Residency Program, Pennsylvania, USA.
Am Fam Physician. 1996 Dec;54(8):2457-9.
Azelaic acid is another option for the topical treatment of mild to moderate inflammatory acne vulgaris. It offers effectiveness similar to that of other agents without the systemic side effects of oral antibiotics or the allergic sensitization of topical benzoyl peroxide and with less irritation than tretinoin. Azelaic acid is less expensive than certain other prescription acne preparations, but it is much more expensive than nonprescription benzoyl peroxide preparations. Whether it is safe and effective when used in combination with other agents is not known.
壬二酸是局部治疗轻至中度寻常性炎性痤疮的另一种选择。它的疗效与其他药物相似,没有口服抗生素的全身性副作用,也没有局部使用过氧化苯甲酰引起的过敏致敏反应,而且与维甲酸相比刺激性更小。壬二酸比某些其他处方痤疮制剂便宜,但比非处方过氧化苯甲酰制剂贵得多。与其他药物联合使用时是否安全有效尚不清楚。