Gordova L A, Egorova V V, Nikitina A A, Timofeeva N M, Tsvetkova V A
Fiziol Zh Im I M Sechenova. 1996 Mar;82(3):27-35.
The maximal activity of membrane enzymes (carbohydrases, alkaline phosphatase, aminopeptidase) was demonstrated in the evening, but that of cytosolic dipeptidases--at night and at day. This is possibly connected with the different functions of the enzymes--digestive or catabolic, resp. The circadian rhythm did not depend on functional states. The circadian rhythms of the enzymes activities were more expressed in the epithelial layer of the small intestine than in the subepithelial (stromal and muscle-serosal) ones.
膜酶(碳水化合物酶、碱性磷酸酶、氨肽酶)的最大活性在傍晚时表现出来,而胞质二肽酶的最大活性则在夜间和白天都有。这可能与酶的不同功能有关——分别是消化或分解代谢功能。昼夜节律并不取决于功能状态。酶活性的昼夜节律在小肠上皮层比在上皮下层(基质和肌浆膜层)表现得更明显。