Gascon G G
Department of Neurology, Brown University, Rhode Island Hospital, Providence, USA.
Semin Pediatr Neurol. 1996 Dec;3(4):260-9. doi: 10.1016/s1071-9091(96)80030-1.
Subacute sclerosing panencephalitis (SSPE), a neurodegenerative disease caused by a persistent "slow virus infection" with a mutated measles virus, is endemic in much of the developing world. Its incidence will increase in the USA, not only in immigrants, but also because of the 1988-1990 measles epidemic. This report reviews the pathogenesis, clinical and laboratory diagnosis, and future perspectives in treatment and prevention.
亚急性硬化性全脑炎（SSPE）是一种由变异麻疹病毒持续“慢病毒感染”引起的神经退行性疾病，在许多发展中国家呈地方性流行。在美国，其发病率将会上升，不仅在移民中，也因1988 - 1990年的麻疹流行。本报告回顾了其发病机制、临床及实验室诊断以及治疗和预防的未来前景。
