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亚急性硬化性全脑炎

Subacute sclerosing panencephalitis.

作者信息

Gascon G G

机构信息

Department of Neurology, Brown University, Rhode Island Hospital, Providence, USA.

出版信息

Semin Pediatr Neurol. 1996 Dec;3(4):260-9. doi: 10.1016/s1071-9091(96)80030-1.

Abstract

Subacute sclerosing panencephalitis (SSPE), a neurodegenerative disease caused by a persistent "slow virus infection" with a mutated measles virus, is endemic in much of the developing world. Its incidence will increase in the USA, not only in immigrants, but also because of the 1988-1990 measles epidemic. This report reviews the pathogenesis, clinical and laboratory diagnosis, and future perspectives in treatment and prevention.

摘要

亚急性硬化性全脑炎(SSPE)是一种由变异麻疹病毒持续“慢病毒感染”引起的神经退行性疾病,在许多发展中国家呈地方性流行。在美国,其发病率将会上升,不仅在移民中,也因1988 - 1990年的麻疹流行。本报告回顾了其发病机制、临床及实验室诊断以及治疗和预防的未来前景。

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