Réfabert L, Rambaud C, Mamou-Mani T, Scheinmann P, de Blic J
Service de Pneumologie et d'Allergologie Pédiatriques, Hôpital Necker-Enfants Malades, Paris, France.
J Pediatr. 1996 Dec;129(6):913-5. doi: 10.1016/s0022-3476(96)70038-0.
We evaluated CD1a-positive cells in bronchoalveolar lavage samples from children with Langerhans cell histiocytosis (LCH). All children with multifocal LCH and pulmonary symptoms scored higher than 5% (30.6% +/- 7.2%), whereas those with other lung disorders scored much less than 5%. In children with multifocal LCH, bronchoalveolar lavage fluid abnormalities can precede pulmonary symptoms. During chemotherapy the CD1a-positive cell count lends to decrease.
我们评估了朗格汉斯细胞组织细胞增多症（LCH）患儿支气管肺泡灌洗样本中的CD1a阳性细胞。所有多灶性LCH且有肺部症状的患儿得分高于5%（30.6%±7.2%），而患有其他肺部疾病的患儿得分远低于5%。在多灶性LCH患儿中，支气管肺泡灌洗液异常可先于肺部症状出现。化疗期间，CD1a阳性细胞计数往往会下降。
