Barrington K J, Finer N, Li D
Perinatal Research Centre, University of Alberta, Edmonton, Canada.
J Pediatr. 1996 Dec;129(6):934-40. doi: 10.1016/s0022-3476(96)70044-6.
There may be a relationship between undiagnosed, ongoing apnea occurring at discharge in infants of very low birth weight and sudden infant death syndrome.
To describe patterns of apnea in former very low birth weight (< 1251 gm) infants thought to be ready for hospital discharge, and to determine the relationship between apnea at discharge and later adverse events-in particular, apparent life-threatening events (ALTEs) and sudden infant death syndrome.
One hundred eighty-seven infants had 24-hour (four-channel) recordings scored for apnea (> 12 seconds in duration) frequency, type, and duration. Infants were followed by telephone interview at 2, 4, and 6 months after discharge from the hospital.
Ninety-one percent of recordings displayed significant apnea, the majority of episodes of apnea were obstructive, and about half occurred during feedings. Infants had as many as 43 episodes in a 24-hour period, with a maximum duration of 62 seconds. There was no relationship between severity of pre-discharge episodes of apnea and ALTEs. No infants died during follow-up.
Predischarge multichannel recordings may identify infants with apnea that is not otherwise clinically apparent but do not predict the risk of an ALTE.
极低出生体重儿出院时存在未被诊断出的持续性呼吸暂停，这可能与婴儿猝死综合征有关。
描述那些被认为已准备好出院的 former 极低出生体重（<1251克）婴儿的呼吸暂停模式，并确定出院时的呼吸暂停与后期不良事件之间的关系，特别是明显危及生命事件（ALTEs）和婴儿猝死综合征。
对187名婴儿进行24小时（四通道）记录，对呼吸暂停（持续时间>12秒）的频率、类型和持续时间进行评分。出院后2个月、4个月和6个月通过电话访谈对婴儿进行随访。
91%的记录显示有明显的呼吸暂停，大多数呼吸暂停发作是阻塞性的，约一半发生在喂食期间。婴儿在24小时内呼吸暂停发作多达43次，最长持续时间为62秒。出院前呼吸暂停发作的严重程度与明显危及生命事件之间没有关系。随访期间没有婴儿死亡。
出院前的多通道记录可能识别出临床上未表现出呼吸暂停的婴儿，但无法预测明显危及生命事件的风险。
