Daniel C R, Daniel M P, Daniel C M, Sullivan S, Ellis G
University of Mississippi Medical Center, Jackson, USA.
Cutis. 1996 Dec;58(6):397-401.
We report here on two retrospective studies conducted between 1982 and 1995 in 137 patients with clinical evidence of chronic paronychia or onycholysis. The purpose of the studies was to determine what factors played a role in these nail disorders. The culture results indicated that yeast commonly grew from the cultured material. Significant contact irritant exposure was frequently found. These findings and our experience suggest that the resolution of chronic paronychia and onycholysis depends on avoiding exposure to contact irritants and on appropriate treatment of any underlying fungal infection. To accomplish this latter goal, it is important to select a broad-spectrum antifungal agent that is effective against yeasts as well as other fungal pathogens.
我们在此报告1982年至1995年间对137例有慢性甲沟炎或甲剥离临床证据患者进行的两项回顾性研究。这些研究的目的是确定哪些因素在这些指甲疾病中起作用。培养结果表明，酵母菌通常从培养材料中生长出来。经常发现有明显的接触性刺激物暴露。这些发现以及我们的经验表明，慢性甲沟炎和甲剥离的解决取决于避免接触接触性刺激物以及对任何潜在真菌感染进行适当治疗。为实现后一个目标，选择一种对酵母菌以及其他真菌病原体有效的广谱抗真菌剂很重要。
