Groenen P A, Makhdoum M, van den Brink J L, Stollman M H, Snik A F, van den Broek P
Department of Otorhinolaryngology, University Hospital Nijmegen, The Netherlands.
Acta Otolaryngol. 1996 Nov;116(6):785-90. doi: 10.3109/00016489609137926.
Electrically evoked brainstem responses (EABR) and event-related cortical potentials were recorded in seven postlingually deaf adults who were experienced users of a Nucleus multichannel cochlear implant. The patients were divided into two subgroups: good performers and moderate performers. Poor EABR were found in two of the moderate performers. The latencies and amplitudes of the cortical N1 P2 complex in the good performers were within the same range as those of subjects with normal hearing, but were deviant in the group of moderate performers. This may indicate disturbed cochleotopical organization of the auditory cortex in the latter group. P300 measurements in the good performers showed normal latencies, whereas in the moderate performers they were prolonged. The results suggest that the outcomes of electrophysiological measurements to assess the integrity of a patient's auditory neural system on a brainstem and a cortical level, are related to the patient's performance with the cochlear implant.
对7名使用Nucleus多通道人工耳蜗的语后聋成年人记录了电诱发脑干反应（EABR）和事件相关皮层电位。患者被分为两个亚组：表现良好者和表现中等者。在两名表现中等者中发现了较差的EABR。表现良好者的皮层N1 P2复合波的潜伏期和波幅与听力正常受试者的在同一范围内，但在表现中等者组中则有偏差。这可能表明后一组听觉皮层的耳蜗拓扑组织受到干扰。表现良好者的P300测量显示潜伏期正常，而表现中等者的则延长。结果表明，在脑干和皮层水平评估患者听觉神经系统完整性的电生理测量结果与患者使用人工耳蜗的表现相关。
