Makhdoum M J, Groenen P A, Snik A F, van den Broek P
Department of Otorhinolaryngology, University Hospital Nijmegen, The Netherlands.
Scand Audiol. 1998;27(1):13-20. doi: 10.1080/010503998419650.
Several electrophysiological techniques have been used to supplement behavioural measurements in the evaluation of the benefit of cochlear implantation, namely the electrically evoked auditory brainstem response (EABR), electrically evoked middle latency response (EMLR) and electrically evoked late latency response (EALR). To study the interdependence of these responses, the present paper deals with a combination of EABR, EMLR and EALR measurements obtained from 15 postlingually deaf subjects implanted with the Nucleus multichannel device at the University Hospital Nijmegen. In particular, we investigated whether there were intercorrelations between amplitude and latencies of the evoked potential peaks and/or correlations with long-term speech perception scores. Significant correlations were found between the peak V amplitude of the EABR and the NaPa and NbPb amplitudes of the EMLR. No significant correlation was found between the EABR and EMLR amplitudes on the one hand and EALR peak amplitudes on the other. In addition, no significant correlations were found between any of the EABR or EMLR peak amplitudes and speech perception test results. A moderate but significant relation was found between the EALR peak amplitude and speech perception test results. Unlike latencies of earlier peaks, the latency of the EALR peak P2 was significantly related to the speech perception scores.
在评估人工耳蜗植入的益处时，已经使用了几种电生理技术来补充行为测量，即电诱发听觉脑干反应（EABR）、电诱发中潜伏期反应（EMLR）和电诱发长潜伏期反应（EALR）。为了研究这些反应之间的相互依存关系，本文探讨了从奈梅亨大学医院15名植入Nucleus多通道装置的语后聋受试者获得的EABR、EMLR和EALR测量结果的组合。特别是，我们研究了诱发电位峰值的幅度和潜伏期之间是否存在相互关联，以及与长期言语感知分数之间是否存在关联。发现EABR的V波峰值幅度与EMLR的NaPa和NbPb幅度之间存在显著相关性。一方面，EABR和EMLR幅度与另一方面的EALR峰值幅度之间未发现显著相关性。此外，EABR或EMLR的任何峰值幅度与言语感知测试结果之间均未发现显著相关性。发现EALR峰值幅度与言语感知测试结果之间存在适度但显著的关系。与早期峰值的潜伏期不同，EALR峰值P2的潜伏期与言语感知分数显著相关。
