Ruggieri V L
Servicio de Neurología, Hospital de Pediatría Garrahan, Buenos Aires, Argentina.
Rev Neurol. 1996 Nov;24(135):1451-5.
In the past decade, notable advances have been made with regard to understanding the clinical, biological and epidermological aspects of the basic disorders of development (TPD), particularly autism. Nevertheless, our knowledge of the neurobiological basis is still limited. This has impeded the development of drugs which correct the defect and cure the illness. Although there is no perfect drug, in recent years clinico-pharmacological research has made it possible to use drugs which have been very helpful in correcting the symptoms associated with these disorders. These drugs have permitted a better therapeutic approach and improved family and social integration of these children (in the family and in society). We will proceed to analyze some of the drugs shown to be useful for treatment of children with TPD.
在过去十年中，在理解发育基本障碍（TPD），尤其是自闭症的临床、生物学和流行病学方面取得了显著进展。然而，我们对其神经生物学基础的了解仍然有限。这阻碍了能够纠正缺陷并治愈疾病的药物的研发。虽然没有完美的药物，但近年来临床药理学研究已使得使用对纠正与这些障碍相关的症状非常有帮助的药物成为可能。这些药物带来了更好的治疗方法，并改善了这些儿童在家庭和社会中的家庭及社会融合情况。我们将着手分析一些已证明对治疗TPD儿童有用的药物。
