MMWR Morb Mortal Wkly Rep. 1996 Dec 13;45(49):1076-9.
In 1988, the Western Pacific Region of the World Health Organization (WHO) adopted a resolution to eradicate poliomyelitis from the region by the end of 1995. The People's Republic of China has made rapid progress toward this goal by implementing the four WHO-recommended strategies for polio eradication: 1) achieving and maintaining high routine vaccination coverage levels among children aged < 1 year with at least three doses of oral poliovirus vaccine (OPV); 2) administering supplementary doses of OPV to all young children during National Immunization Days (NIDs) to rapidly interrupt poliovirus transmission; 3) establishing sensitive systems of surveillance for acute flaccid paralysis (AFP) and virologic surveillance for poliovirus; and 4) conducting "supplementary immunization activities" (SIAs)--localized campaigns targeted at high-risk areas where poliovirus transmission is most likely to persist at low levels. These strategies have resulted in the apparent interruption of wild poliovirus transmission in China. In 1995, no indigenous wild polioviruses were deteced despite a strengthened surveillance system. This report describes progress toward achievement of the eradication goal and updates the status of polio-eradication efforts in China during 1990-1996.
1988年,世界卫生组织(WHO)西太平洋区域通过了一项决议,要在1995年底前在该区域根除脊髓灰质炎。中华人民共和国通过实施世界卫生组织推荐的四项根除脊髓灰质炎战略,在实现这一目标方面取得了迅速进展:1)使1岁以下儿童口服脊髓灰质炎疫苗(OPV)至少接种三剂,实现并维持高常规疫苗接种覆盖率;2)在全国免疫日(NIDs)期间给所有幼儿补充接种OPV,以迅速阻断脊髓灰质炎病毒传播;3)建立急性弛缓性麻痹(AFP)敏感监测系统和脊髓灰质炎病毒病毒学监测系统;4)开展“补充免疫活动”(SIAs)——针对脊髓灰质炎病毒传播最有可能在低水平持续存在的高危地区开展的局部运动。这些战略已使中国境内野生脊髓灰质炎病毒传播明显阻断。1995年,尽管监测系统得到加强,但未检测到本土野生脊髓灰质炎病毒。本报告描述了在实现根除目标方面取得的进展,并更新了1990 - 1996年期间中国根除脊髓灰质炎工作的状况。