Milde E J, Aarli J, Larsen J L
Scand J Rheumatol. 1977;6(2):118-22. doi: 10.3109/03009747709095433.
Three patients with the combination of long-standing ankylosing spondylitis (AS) and cauda equina syndrome are described and compared with 17 from the literature. The nerve root lesion has been of gradual onset and has since the time of diagnosis either been stationary or progressed slowly. Radicular pain in the feet and legs, and genito-urinary complaints have been the dominant and most disabling symptoms. Typical myelographic findings were expansion of the dural sac and arachnoidal diverticula. There is a highly probable relationship between AS and the neurological syndrome. The pathogenesis is probably related to early arachnoiditis with subsequent loss of meningeal elasticity. Earlier recognition of the root lesion may result in a more effective treatment.
本文描述了3例长期患有强直性脊柱炎（AS）并伴有马尾综合征的患者，并与文献报道的17例患者进行了比较。神经根病变起病缓慢，自诊断以来病情要么稳定，要么进展缓慢。足部和腿部的神经根性疼痛以及泌尿生殖系统症状是主要且最致残的症状。典型的脊髓造影表现为硬脊膜囊扩张和蛛网膜憩室。AS与神经综合征之间很可能存在关联。其发病机制可能与早期蛛网膜炎以及随后的脑膜弹性丧失有关。更早地识别神经根病变可能会带来更有效的治疗。
