Fledelius H C, Christensen A C
Eye department, Hillerød Sygehus, Denmark.
Br J Ophthalmol. 1996 Oct;80(10):918-21. doi: 10.1136/bjo.80.10.918.
The aim of this study was to find an algorithm of better fit for early eye growth than the linear regression usually advanced.
The analysis is based on previously published around term data, the main material being axial ultrasound measurements in preterm (n = 101) and full term infants (n = 25). The postconceptional age of the infants ranged between 36 and 54 weeks. Previously published Danish data from eyes of aborted fetuses were also used, as were averaged values from the literature regarding eye size at age 1 year (20 mm), 3 years (22 mm), and a presumed 13 year endpoint of 23 mm.
A second order exponential function fitted with the basic data within a standard deviation of 2%.
A simple symbolic expression and tabulated values for eye growth in infancy and childhood were derived. This is clearly of practical value, for example, when following the development of eyes treated for congenital glaucoma or assessing other developmental anomalies and early eye diseases.
本研究的目的是找到一种比通常采用的线性回归更适合早期眼球生长的算法。
该分析基于先前发表的足月左右的数据,主要材料是早产婴儿(n = 101)和足月婴儿(n = 25)的眼轴超声测量值。婴儿的孕龄在36至54周之间。还使用了先前发表的丹麦关于流产胎儿眼睛的数据,以及来自文献的1岁(20毫米)、3岁(22毫米)和假定13岁终点(23毫米)时眼睛大小的平均值。
一个二阶指数函数与基本数据拟合,标准差在2%以内。
得出了婴儿期和儿童期眼球生长的简单符号表达式和表格值。这显然具有实际价值,例如,在跟踪接受先天性青光眼治疗的眼睛的发育情况或评估其他发育异常和早期眼病时。