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裂褶菌Bα1信息素受体基因的等位基因差异

Allelic divergence at B alpha 1 pheromone receptor genes of Schizophyllum commune.

作者信息

Wendland J, Kothe E

机构信息

Dept. Biology, Fachbereich Biologie-Molekulargenetik, Philipps-Universität, Marburg, Germany.

出版信息

FEMS Microbiol Lett. 1996 Dec 15;145(3):451-5. doi: 10.1111/j.1574-6968.1996.tb08615.x.

Abstract

The multiallelic mating type locus B alpha 1 of Schizophyllum commune encodes a pheromone receptor and putative pheromone genes. A comparison of two alleles encoding receptors that share the same specificity B alpha 1 was performed using strains of different geographic origin. The amino acid sequence alignment revealed strong conservation of the largest part of the receptor. Only in the distal C-terminus major amino acid was divergence encountered. This C-terminal region of 117 of the total of 639 amino acids was shown to be unnecessary for function in vivo by transformation experiments.

摘要

裂褶菌的多等位基因交配型位点Bα1编码一种信息素受体和假定的信息素基因。使用不同地理来源的菌株,对编码具有相同特异性Bα1的受体的两个等位基因进行了比较。氨基酸序列比对显示受体的大部分区域具有高度保守性。仅在远端C末端遇到主要氨基酸的差异。通过转化实验表明,在总共639个氨基酸中的这117个C末端区域在体内功能中并非必需。

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