Kretschmann U, Rüther K, Usui T, Zrenner E
Department of Pathophysiology of Vision and Neuro-Ophthalmology, University Eye Hospital, Tübingen, Germany.
Ophthalmic Res. 1996;28(5):303-11. doi: 10.1159/000267919.
The m-sequence stimulation technique that has previously been described allows simultaneous recording of many local electroretinograms (ERGs). For topographical mapping of cone function in the central retina ERG traces from 61 retinal areas were recorded during a 4-min period in 20 normal volunteers and 4 patients with age-related macular degeneration, Stargardt's disease, choroidal atrophy, and polymyalgia associated with visual field loss. The local photopic luminance response was analyzed in each of the 61 areas. In the 2 patients with macular disease central defects were detected, in the remaining patients local defects were found outside the macular region. The method of multifocal ERG recordings provides the possibility of objective testing of visual fields when the outer retinal layers are affected.
先前已描述的m序列刺激技术可同时记录多个局部视网膜电图(ERG)。在20名正常志愿者和4例患有年龄相关性黄斑变性、Stargardt病、脉络膜萎缩以及伴有视野缺损的多肌痛患者中,于4分钟内记录了来自61个视网膜区域的ERG痕迹,以对中央视网膜的视锥细胞功能进行地形图绘制。对61个区域中的每个区域的局部明视觉亮度反应进行了分析。在2例黄斑疾病患者中检测到中央缺损,在其余患者中在黄斑区域外发现了局部缺损。当视网膜外层受到影响时,多焦点ERG记录方法为视野的客观测试提供了可能性。