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肺动脉球囊瓣膜成形术治疗复杂青紫型先天性心脏病的姑息治疗

Pulmonary balloon valvuloplasty in the palliation of complex cyanotic congenital heart disease.

作者信息

Stümper O, Piéchaud J F, Bonhoeffer P, Bonnet D, Aggoun Y, Sidi D, Kachaner J

机构信息

Service de Cardiologie Pédiatrique, Hôpital Necker/Enfants-Malades, Paris, France.

出版信息

Heart. 1996 Oct;76(4):363-6. doi: 10.1136/hrt.76.4.363.

Abstract

OBJECTIVE

To assess the value of pulmonary balloon valvuloplasty in the interim palliation of complex congenital heart disease and pulmonary stenosis in children, who often require numerous palliative operations before definitive surgical repair.

METHODS

Evaluation of pulmonary balloon valvuloplasty procedures performed over a five year period in 18 patients (age 8 days--29 years; mean 5.5 years) with complex cyanotic congenital heart disease.

RESULTS

After pulmonary balloon valvuloplasty oxygen saturation increased from a mean (SD) of 69 (7.5)% to 83 (7.0)% (P < 0.001). Mean pulmonary artery pressure increased from a mean (SD) of 11.3 (3.8) mm Hg to 15.7 (3.9) mm Hg (P < 0.001). Transient complete atrioventricular block occurred in one patient. No other complications were encountered. In 5 patients (28%) there was an inadequate improvement in cyanosis compared with pre-procedure values (72 (4.7)% v 66 (8.1)%). Reasons for failure were increasing infundibular stenosis in three and inadequate mixing in one child. In 13 patients (72%) pulmonary balloon valvuloplasty gave adequate interim palliation over a mean follow up of 1.1 (1.3) years. Oxygen saturation was 81 (5.6)% at last follow up compared with 70 (7.3)% before pulmonary balloon valvuloplasty (P < 0.001).

CONCLUSION

Pulmonary balloon valvuloplasty is a safe and effective technique in the palliation of patients with complex cyanotic congenital heart disease associated with pulmonary valve stenosis.

摘要

目的

评估肺动脉球囊瓣膜成形术在儿童复杂先天性心脏病和肺动脉狭窄的临时姑息治疗中的价值,这类患儿在进行确定性手术修复前通常需要多次姑息性手术。

方法

对18例(年龄8天至29岁;平均5.5岁)患有复杂青紫型先天性心脏病的患者在五年期间进行的肺动脉球囊瓣膜成形术进行评估。

结果

肺动脉球囊瓣膜成形术后,氧饱和度从平均(标准差)69(7.5)%升至83(7.0)%(P<0.001)。平均肺动脉压从平均(标准差)11.3(3.8)mmHg升至15.7(3.9)mmHg(P<0.001)。1例患者出现短暂性完全性房室传导阻滞。未遇到其他并发症。5例患者(28%)与术前相比,青紫改善不足(72(4.7)%对66(8.1)%)。失败原因是3例漏斗部狭窄加重,1例患儿混合不充分。13例患者(72%)在平均1.1(1.3)年的随访中,肺动脉球囊瓣膜成形术提供了足够的临时姑息治疗。末次随访时氧饱和度为81(5.6)%,而肺动脉球囊瓣膜成形术前为70(7.3)%(P<0.001)。

结论

肺动脉球囊瓣膜成形术是治疗伴有肺动脉瓣狭窄的复杂青紫型先天性心脏病患者的一种安全有效的姑息治疗技术。

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