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氯走马茶素:一种来自单花鹿蹄草的新型抗生素。

Chlorochimaphilin: a new antibiotic from Moneses uniflora.

作者信息

Saxena G, Farmer S W, Hancock R E, Towers G H

机构信息

Department of Microbiology at West-East Center, University of British Columbia, Vancouver, Canada.

出版信息

J Nat Prod. 1996 Jan;59(1):62-5. doi: 10.1021/np960006v.

Abstract

A study of the antimicrobial compounds from Moneses uniflora resulted in the isolation of a novel compound, 8-chloro-2,7-dimethyl-1,4-naphthoquinone (8-chlorochimaphilin) (1), together with chimaphilin (2) and 3-hydroxychimaphilin (3) as the antimicrobial components. 2,7-Dimethyl-1,3-dihydroxynaphthyl 4-O-alpha-L-rhamnopyranoside (4) and 2,7-dimethoxy-1,4,8-trihydroxynaphthalene (6) were also isolated and identified.

摘要

一项对单花鹿蹄草抗菌化合物的研究,分离出一种新型化合物8-氯-2,7-二甲基-1,4-萘醌(8-氯马醉木素)(1),同时还有马醉木素(2)和3-羟基马醉木素(3)作为抗菌成分。还分离并鉴定出了2,7-二甲基-1,3-二羟基萘基4-O-α-L-鼠李吡喃糖苷(4)和2,7-二甲氧基-1,4,8-三羟基萘(6)。

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