从海洋扇状真菌 Fusarium spp. PSU-F14 和 PSU-F135 中分离得到蒽醌、环戊酮和萘醌衍生物。
Anthraquinone, cyclopentanone, and naphthoquinone derivatives from the sea fan-derived fungi Fusarium spp. PSU-F14 and PSU-F135.
机构信息
Department of Chemistry and Center for Innovation in Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand.
出版信息
J Nat Prod. 2010 Sep 24;73(9):1507-11. doi: 10.1021/np100282k.
PMID:20815366
Abstract
Five new metabolites, fusaranthraquinone (1), fusarnaphthoquinones A-C (2-4), and fusarone (5), were isolated from the sea fan-derived fungi Fusarium spp. PSU-F14 and PSU-F135 along with 18 known compounds. The structures were elucidated on the basis of spectroscopic evidence. Their antibacterial, antifungal, antimycobacterial, antimalarial, and cytotoxic activities were examined.
摘要
从海洋扇状真菌 Fusarium spp. PSU-F14 和 PSU-F135 中分离得到了 5 种新的代谢产物：呋咱萘醌（1）、呋咱萘醌 A-C（2-4）和呋咱酮（5），以及 18 种已知化合物。基于光谱证据阐明了它们的结构。测试了它们的抗菌、抗真菌、抗分枝杆菌、抗疟原虫和细胞毒性活性。
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