Roessingh P H, van Loon A M, Lammers J W, Hoepelman I M
Academisch Ziekenhuis, Utrecht, Afd. Interne Geneeskunde, onderafd, Infectieziekten en AIDS.
Ned Tijdschr Geneeskd. 1996 Nov 30;140(48):2406-10.
To determine the prevalence of viruses and atypical pathogens as causes of acute severe exacerbations of chronic bronchitis.
Retrospective.
University Hospital Utrecht, the Netherlands.
In 4 studies with 305 patients with severe type-1 exacerbations (increase of dyspnoea, of sputum volume and of sputum purulence) serological tests for viral and atypical pathogens were performed.
Positive serology for viral infections was seen in 18 (5.9%) patients and for the atypical pathogens in 12 (3.9%) patients.
Since viruses and atypical pathogens are the cause of the exacerbation in only few cases, clinical signs can be used in decision-making whether or not to prescribe antibiotics in acute exacerbations of chronic bronchitis.
确定病毒和非典型病原体作为慢性支气管炎急性重度加重病因的患病率。
回顾性研究。
荷兰乌得勒支大学医学中心。
对4项研究中的305例重度1型加重（呼吸困难、痰量和痰脓性增加）患者进行病毒和非典型病原体的血清学检测。
18例（5.9%）患者病毒感染血清学检测呈阳性，12例（3.9%）患者非典型病原体血清学检测呈阳性。
由于病毒和非典型病原体仅在少数病例中是加重的病因，因此在慢性支气管炎急性加重时，临床体征可用于决定是否使用抗生素。
