Chonan O, Takahashi R, Yasui H, Watanuki M
Yakult Central Institute for Microbiological Research, Tokyo, Japan.
Biosci Biotechnol Biochem. 1996 Oct;60(10):1735-7. doi: 10.1271/bbb.60.1735.
Magnesium deficiency was induced in male Wistar rats by adding an excess of phosphorous and calcium to the diet (1.195 g of phosphorous and 1.04 g of calcium/100 g of diet). Feeding of these animals with a diet containing beta 1-->4 linked galactooligosaccharides (4'-GOS) (5 g of 4'-GOS/100 g of diet) increased the apparent magnesium absorption ratios and the concentrations of magnesium in the serum and femur, and reduced accumulation of calcium in the kidney and heart. We speculate that the use of magnesium increased by feeding 4'-GOS to a limited extent prevented the lower magnesium status and the severity of calcification of the kidney and heart caused by excess dietary phosphorous and calcium.
通过在饮食中添加过量的磷和钙（每100克饮食中含1.195克磷和1.04克钙）诱导雄性Wistar大鼠出现镁缺乏。用含有β1→4连接的低聚半乳糖（4'-GOS）的饮食（每100克饮食含5克4'-GOS）喂养这些动物，可提高表观镁吸收比率以及血清和股骨中的镁浓度，并减少肾脏和心脏中钙的积累。我们推测，通过喂食4'-GOS在一定程度上增加镁的利用，可预防因饮食中磷和钙过量导致的较低镁状态以及肾脏和心脏钙化的严重程度。
