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杜氏肌营养不良症患者后路脊柱融合术后的并发症

Complications after posterior spinal fusion in Duchenne's muscular dystrophy.

作者信息

Ramirez N, Richards B S, Warren P D, Williams G R

机构信息

Department of Orthopaedics, Texas Scottish Rite Hospital for Children, Dallas 75219, USA.

出版信息

J Pediatr Orthop. 1997 Jan-Feb;17(1):109-14.

PMID:8989712
Abstract

Patients with Duchenne's muscular dystrophy often develop progressive scoliosis. Should spinal stabilization be necessary, these patients are considered at high risk for surgically related complications. This retrospective study of 30 patients with Duchenne's examined the prevalence and types of complications associated with posterior spinal fusion and determined the percentage of patients who lived > or = 2 years beyond surgery. Major complications related to cardiopulmonary compromise, infection, or hardware complications occurred in 27%, and minor complications occurred in another 16%. Seventy-seven percent of the patients lived > or = 2 years beyond their surgery. The majority of patients and their families, including half of those who had major complications, reported that surgery resulted in an improvement in their quality of life. Although complications are common, the benefits realized by the patient with Duchenne's muscular dystrophy with scoliosis reinforce the importance of surgical stabilization.

摘要

杜兴氏肌营养不良症患者常出现进行性脊柱侧弯。若有必要进行脊柱稳定手术,这些患者被认为发生手术相关并发症的风险很高。这项对30例杜兴氏患者的回顾性研究,调查了与后路脊柱融合相关的并发症的发生率和类型,并确定了术后存活≥2年的患者百分比。与心肺功能不全、感染或硬件相关并发症有关的主要并发症发生率为27%,次要并发症发生率为16%。77%的患者术后存活≥2年。大多数患者及其家属,包括半数发生主要并发症的患者,报告称手术改善了他们的生活质量。虽然并发症很常见,但杜兴氏肌营养不良症合并脊柱侧弯患者所获得的益处,强化了手术稳定治疗的重要性。

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