戊二醛作为生物假体和药物递送基质中的固定剂。
Glutaraldehyde as a fixative in bioprostheses and drug delivery matrices.
作者信息
Jayakrishnan A, Jameela S R
机构信息
Polymer Chemistry Division, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.
出版信息
Biomaterials. 1996 Mar;17(5):471-84. doi: 10.1016/0142-9612(96)82721-9.
PMID:8991478
Abstract
The use of glutaraldehyde as a fixative in bioprostheses and drug delivery matrices is reviewed. The chemistry of glutaraldehyde cross-linking and its effect on the biological performance of a number of bioprostheses such as tissue heart valves, vascular grafts, pericardial patches, tendon grafts and drug delivery matrices are examined.
摘要
本文综述了戊二醛在生物假体和药物递送基质中作为固定剂的应用。研究了戊二醛交联的化学过程及其对多种生物假体（如组织心脏瓣膜、血管移植物、心包补片、肌腱移植物）和药物递送基质生物学性能的影响。
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