Vitvitskiĭ V N, Bakhitova L M, Soboleva L S, Shevchenko V A
Izv Akad Nauk Ser Biol. 1996 Jul-Aug(4):495-8.
The effect of K2Cr2O7 and (CH3COO)2Pb on the mutagenic activity of gamma rays was studied by a micronucleus test in mouse bone marrow polychromatocytes. Acute and chronic combined actions of the two factors were investigated. Chromium ions (VI) enhanced mutagenic effects of gamma rays in both acute and chronic experiments. In the acute experiments lead ions (II) below 15 mg/kg body weight decreased the number of gamma-ray-induced micronuclei, while higher doses increased it. Chronic combined action of lead ions (III) and gamma rays inhibited mutagenic activity of radiation.
通过小鼠骨髓多染性红细胞微核试验，研究了重铬酸钾（K2Cr2O7）和醋酸铅（(CH3COO)2Pb）对γ射线诱变活性的影响。研究了这两种因素的急性和慢性联合作用。在急性和慢性实验中，六价铬离子均增强了γ射线的诱变作用。在急性实验中，体重低于15mg/kg的二价铅离子可减少γ射线诱导的微核数量，而较高剂量则会增加微核数量。三价铅离子与γ射线的慢性联合作用抑制了辐射的诱变活性。
