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[预防非胰岛素依赖型糖尿病的可能性]

[The possibility of preventing non-insulin dependent diabetes].

作者信息

Fuchs H

机构信息

Kliniki Endokrynologii, Nadciśnienia, Tetniczego i Przemiany Materii, Pomorskiej Akademii Medycznej w Szczecinie.

出版信息

Przegl Lek. 1996;53(9):668-71.

PMID:8992535
Abstract

High and rapid growing up incidence of non-insulin-dependent diabetes mellitus (NIDDM) leading to severe chronic complications and significant reduction of life expectancy, as well as a huge rise of direct and indirect costs connected with the disease oblige to search for methods of its prevention. Scientific basis of the prevention grounded on a knowledge of genetic and environmental pathogenetic factors as well as natural history of NIDDM does exist. The article discussed shortly the strategy of prevention based on attempts of life style (diet, physical exercise) and pharmacological interventions. Actually, primary prevention of NIDDM seems to be hypothesis requiring further testing, but the possibility and necessity of secondary and tertiary prevention is incontroversible.

摘要

非胰岛素依赖型糖尿病(NIDDM)的发病率高且增长迅速,会导致严重的慢性并发症并显著缩短预期寿命,同时与该疾病相关的直接和间接成本大幅上升,这就促使人们寻找其预防方法。基于对遗传和环境致病因素以及NIDDM自然病史的了解,确实存在预防的科学依据。本文简要讨论了基于生活方式(饮食、体育锻炼)和药物干预尝试的预防策略。实际上,NIDDM的一级预防似乎是一个需要进一步验证的假设,但二级和三级预防的可能性和必要性是无可争议的。

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