抗菌药咪拉米司亭具有很强的抗艾滋病毒特性。
Antiseptic myramistin possesses the strong anti-HIV properties.
作者信息
Kryvorutchenko Iu L, Kryvosheïn Iu S, Andronovs'ka I B, Marennykova S S, Stepanova L H, Nosyk D N, Kalnina L B, Rud'ko A P
机构信息
Department of Microbiology, Crimean Medical Institute, Simferopol.
出版信息
Mikrobiol Z. 1996 Sep-Oct;58(5):90-2.
The anti-HIV properties of cation detergent myramistin were studied. The dose-dependent slowing down both of the HIV antigens accumulation in supernatants and the virus-dependent cell death was shown at myramistin concentrations 30 micrograms/ml and 50 micrograms/ml in the MT-4 cell line. Simultaneous addition of the trace amount of the detergents and HIV-1 to the cells of Jurkat-tat line did not stimulate the HIV p24 production for 4 days of the experiment.
研究了阳离子去污剂米拉美斯汀的抗HIV特性。在MT - 4细胞系中，当米拉美斯汀浓度为30微克/毫升和50微克/毫升时，可呈现剂量依赖性地减缓上清液中HIV抗原的积累以及病毒依赖性细胞死亡。在实验的4天里，向Jurkat - tat细胞系同时添加痕量去污剂和HIV - 1并未刺激HIV p24的产生。
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