鉴定Rox3作为中介体和RNA聚合酶II全酶的一个组成部分。
Identification of Rox3 as a component of mediator and RNA polymerase II holoenzyme.
作者信息
Gustafsson C M, Myers L C, Li Y, Redd M J, Lui M, Erdjument-Bromage H, Tempst P, Kornberg R D
机构信息
Department of Structural Biology, Stanford University School of Medicine, California 94305-5400, USA.
出版信息
J Biol Chem. 1997 Jan 3;272(1):48-50. doi: 10.1074/jbc.272.1.48.
PMID:8995225
Abstract
Yeast Rox3 protein, implicated by genetic evidence in both negative and positive transcriptional regulation, is identified as a mediator subunit by peptide sequence determination and is shown to copurify and co-immunoprecipitate with RNA polymerase II holoenzyme.
摘要
酵母Rox3蛋白，遗传学证据表明其在负转录调控和正转录调控中均有涉及，通过肽序列测定被鉴定为一种中介亚基，并显示与RNA聚合酶II全酶共纯化和共免疫沉淀。
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