分枝杆菌属和诺卡氏菌属中存在F420依赖性葡萄糖-6-磷酸脱氢酶，但链霉菌属、棒状杆菌属和产甲烷古菌中不存在。

Presence of F420-dependent glucose-6-phosphate dehydrogenase in Mycobacterium and Nocardia species, but absence from Streptomyces and Corynebacterium species and methanogenic Archaea.

作者信息

Purwantini E, Gillis T P, Daniels L

机构信息

Department of Microbiology, University of Iowa, Iowa City 52242, USA.

出版信息

FEMS Microbiol Lett. 1997 Jan 1;146(1):129-34. doi: 10.1111/j.1574-6968.1997.tb10182.x.

DOI:10.1111/j.1574-6968.1997.tb10182.x

PMID:8997717

Abstract

A range of organisms known to contain F420 or to be relatives of mycobacteria were examined for F420-dependent glucose-6-phosphate dehydrogenase (FGD) and NADP-dependent glucose-6-phosphate dehydrogenase (NADP-G6PD) activities. All free-growing Mycobacterium species examined (including a virulent Mycobacterium tuberculosis strain) had FGD activities of 0.014-0.418 mumol min-1 mg protein-1, and NADP-G6PD activities of 0.013-0.636 mumol min-1 mg-1. Armadillo-grown Mycobacterium leprae had FGD activity of 0.008 mumol min-1 mg-1, but no detectable NADP-G6PD activity. Nocardia species also had FGD activity (0.088-0.154 mumol min-1 mg-1). Streptomyces and Corynebacterium species had no FGD, but had NADP-G6PD. Methanogenic Archaea had neither activity.

摘要

对一系列已知含有F420或为分枝杆菌亲属的生物体进行了F420依赖性葡萄糖-6-磷酸脱氢酶（FGD）和NADP依赖性葡萄糖-6-磷酸脱氢酶（NADP-G6PD）活性检测。所有检测的自由生长分枝杆菌物种（包括一株毒力结核分枝杆菌菌株）的FGD活性为0.014 - 0.418 μmol min⁻¹ mg蛋白⁻¹，NADP-G6PD活性为0.013 - 0.636 μmol min⁻¹ mg⁻¹。犰狳体内生长的麻风分枝杆菌FGD活性为0.008 μmol min⁻¹ mg⁻¹，但未检测到NADP-G6PD活性。诺卡氏菌属也有FGD活性（0.088 - 0.154 μmol min⁻¹ mg⁻¹）。链霉菌属和棒状杆菌属没有FGD，但有NADP-G6PD。产甲烷古菌两种活性均无。