Bojsen-Møller M
Acta Pathol Microbiol Scand A. 1977 Jul;85(4):447-54.
Six cases of primary malignant melanoma of the leptomeninges and brain are reported. Three were diagnosed histologically at surgery, three at autopsy. Four presented as solitary brain tumours which is unusual compared to other reported cases. In all six there was infiltration of the leptomeninges which must be regarded as the site of origin. Three of the cases have had a relatively long survival, two of them have died 2 years after the operation, and the third patient is still alive 18 months after surgery. It is suggested that the frequency of these tumours is underestimated on account of their resemblance to astroblastomas and poorly differentiated astrocytomas, and because biopsies are not always taken from small and atypical haematomas.
报告了6例软脑膜和脑原发性恶性黑色素瘤。3例在手术时经组织学诊断，3例在尸检时诊断。4例表现为孤立性脑肿瘤，与其他报道的病例相比这并不常见。在所有6例中，软脑膜均有浸润，这必须被视为起源部位。其中3例存活时间相对较长，2例在手术后2年死亡，第3例患者在手术后18个月仍然存活。有人认为，由于这些肿瘤与成星形细胞瘤和低分化星形细胞瘤相似，且活检并非总是取自小的非典型血肿，因此这些肿瘤的发生率被低估了。
