Amarti A, Bernoussi Z, Aghzadi A, Khamlichi A, Saidi A
Laboratoire d'Anatomie pathologique, Hôpital des spécialités, RABAT Instituts, Maroc.
Arch Anat Cytol Pathol. 1998;46(3):188-92.
We report 4 cases of intracranial melanoma without any clinically diagnosed extracerebral location. These tumors presented at different sites and had different histological aspects. Intracytoplasmic melanin was present in all cases, immunohistochemistry confirmed the diagnosis and eliminated a possible glioblastoma or metastatic carcinoma. Clinical and pathologic characteristics of primary pigmented lesions of the CNS are discussed with particular interest in diagnostic difficulties and histogenesis of these lesions.
我们报告了4例临床上未诊断出脑外转移的颅内黑色素瘤病例。这些肿瘤位于不同部位，具有不同的组织学表现。所有病例均存在胞浆内黑色素，免疫组化确诊了诊断，并排除了可能的胶质母细胞瘤或转移癌。本文讨论了中枢神经系统原发性色素性病变的临床和病理特征，特别关注这些病变的诊断难点和组织发生。
