Rezvukhin A I, Shalaurova I Iu, Berezovskaia E V
Vopr Med Khim. 1996 Jan-Mar;42(1):59-64.
The spectra of blood fatty acids, the true diet and the immune system were explored in 40-54-aged male populations of Siberia and Chukotka. There were differences in the serum levels of omega 3, and omega 6-polyunsaturated fatty acids (PUFA) in the residents od the areas under study. The blood concentration of omega 3-PUFA was significantly higher in the Chukchi than that in Novosibirsk residents, which is associated with the fact the Chuchotka inhabitants consume sea fish and products, which are rich in eicosapentaenoic and docosahexaenic acids. Excess omega 3-PUFA was found to produce an immunosuppressive effect in the body: in the subjects having high serum omega 3-PUFA concentrations there was a reduced count of T lymphocyte, killer cells, responsible for cell-mediated immunity, as compared to those having low omega 3-PUFA concentrations.
对西伯利亚和楚科奇地区40至54岁男性人群的血液脂肪酸谱、实际饮食和免疫系统进行了研究。在所研究地区的居民中，ω-3和ω-6多不饱和脂肪酸（PUFA）的血清水平存在差异。楚科奇人的ω-3-PUFA血液浓度显著高于新西伯利亚居民，这与楚科奇居民食用富含二十碳五烯酸和二十二碳六烯酸的海鱼及产品这一事实有关。研究发现，过量的ω-3-PUFA会在体内产生免疫抑制作用：与ω-3-PUFA浓度低的受试者相比，血清ω-3-PUFA浓度高的受试者中，负责细胞介导免疫的T淋巴细胞、杀伤细胞数量减少。
