Lipshitz J
Am J Obstet Gynecol. 1977 Sep 1;129(1):31-6. doi: 10.1016/0002-9378(77)90814-6.
Severe fetal distress in labor is an obstetric emergency which may result in the delivery of a severely asphyxiated baby or even death of the fetus. This problem may be compounded by a hurried mechanical vaginal delivery or by delay before a cesarean section can be performed. The rationale for using a beta sympathomimetric drug as a temporizing measure in the treatment of fetal distress to prevent deterioration in and even to improve the condition of the fetus before delivery is discussed. Six cases are described in which hexoprenaline (Ipradol), a beta2-selective sympathomimetic drug, has been administered as a 10 microgram intravenous bolus in the treatment of acute fetal distress in labor.
分娩时的严重胎儿窘迫是一种产科急症,可能导致严重窒息婴儿的出生,甚至胎儿死亡。匆忙进行机械性阴道分娩或在剖宫产手术前延误可能会使这个问题更加复杂。本文讨论了使用β-拟交感神经药物作为临时措施治疗胎儿窘迫,以防止分娩前胎儿状况恶化甚至改善其状况的基本原理。文中描述了6例使用β2选择性拟交感神经药物海索那林(依普拉多)以10微克静脉推注治疗分娩时急性胎儿窘迫的病例。