Kuturec M, Emoto S E, Sofijanov N, Dukovski M, Duma F, Ellenberg J H, Hirtz D G, Nelson K B
National Institute of Neurological Disorders and Stroke (NINDS), Bethesda, Maryland 20892-9020, USA.
Clin Pediatr (Phila). 1997 Jan;36(1):31-6. doi: 10.1177/000992289703600105.
We examined the predictive value of a paroxysmal EEG in children with febrile seizures seen at the University Pediatric Clinic, Skopje, Macedonia, between 1982 and 1984. This was the only facility providing EEG or neurologic consultation for children in Macedonia, and almost all children in the area who experienced a febrile seizure were referred to this facility. EEGs were classified as epileptiform if they contained spikes and sharp waves or spike wave complexes, which were either focal or generalized, and were considered abnormal for age and state. Nonspecifically abnormal was defined as focal or generalized slowing excessive for age and state. Follow-up visits were scheduled at 6-month intervals; mean follow-up time was approximately 23 months. In order to determine whether clearly abnormal EEG features would predict recurrences, we compared the recurrences in 170 children with initial normal-appearing EEGs with 99 children with initial paroxysmal EEGs. There was no significant difference in risk of recurrence of febrile seizures between the two groups; increase in recurrence risk was determined primarily by younger age. The EEG did not add information regarding the likelihood of recurrence of febrile seizures.
我们研究了1982年至1984年间在马其顿斯科普里大学儿科诊所就诊的热性惊厥儿童中阵发性脑电图的预测价值。这是马其顿唯一一家为儿童提供脑电图或神经科会诊的机构，该地区几乎所有经历过热性惊厥的儿童都被转诊到了这家机构。如果脑电图包含尖波、锐波或尖慢波综合波，无论其为局灶性还是全身性，且对于年龄和状态而言被认为异常，则将其分类为癫痫样脑电图。非特异性异常被定义为对于年龄和状态而言局灶性或全身性的过度减慢。随访安排为每隔6个月进行一次；平均随访时间约为23个月。为了确定明显异常的脑电图特征是否能预测复发，我们比较了170名初始脑电图正常儿童与99名初始阵发性脑电图儿童的复发情况。两组热性惊厥复发风险无显著差异；复发风险增加主要由年龄较小决定。脑电图并未提供有关热性惊厥复发可能性的额外信息。
