Chase H P, Garg S K, Icaza G, Carmain J A, Walravens C F, Marshall G
Department of Pediatrics, Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Denver, USA.
Am J Hypertens. 1997 Jan;10(1):18-23. doi: 10.1016/s0895-7061(96)00260-9.
The purpose of this study was to compare office and 24-h ambulatory blood pressure (ABP) values for adolescent and young adult males and females of Anglo, Hispanic, and African-American descent. One hundred and eighteen healthy subjects (62 females, 56 males) participated, with an ethnic distribution of 50 Anglo, 32 Hispanic, and 36 African-American subjects. All subjects came to the clinic for height, weight, sitting blood pressure (BP), and to begin 24-h ABP monitoring using the SpaceLabs model 90207 automatic noninvasive monitor. The monitor recorded readings every 0.5 h from 06:00 to 22:00 and every hour at night from 22:00 to 06:00. Office systolic and diastolic BP values were higher for all males compared to all females. Mean 24-h, nighttime, and daytime systolic ABP values were also significantly higher for males compared to females. The 24-h mean and daytime systolic ABP values were significantly different by ethnic groups. The African-American subjects always had the highest readings. Mean 24-h diastolic ABP was also significantly different by ethnic groups, with the African-American subjects being higher than the Anglos or the Hispanics. Diastolic ABP (24-h mean, daytime, and nighttime) values (for all subjects combined) increased gradually and varied significantly with age. This study provides preliminary normative data about ABP in an understudied population (ie, teenagers and young adults of different ethnic backgrounds). It also shows that higher blood pressures are present among males and among subjects of African-American descent in the teenage and young adult population.
本研究的目的是比较盎格鲁、西班牙裔和非裔美国青少年及年轻成年男性和女性的诊室血压和24小时动态血压(ABP)值。118名健康受试者(62名女性,56名男性)参与了研究,种族分布为50名盎格鲁人、32名西班牙裔和36名非裔美国人。所有受试者均到诊所测量身高、体重、坐位血压(BP),并开始使用太空实验室90207型自动无创监测仪进行24小时ABP监测。该监测仪在06:00至22:00每0.5小时记录一次读数,夜间22:00至06:00每小时记录一次读数。所有男性的诊室收缩压和舒张压值均高于所有女性。男性的24小时平均、夜间和白天收缩压ABP值也显著高于女性。24小时平均和白天收缩压ABP值在不同种族之间存在显著差异。非裔美国受试者的读数始终最高。24小时平均舒张压ABP在不同种族之间也存在显著差异,非裔美国受试者高于盎格鲁人或西班牙裔。舒张压ABP(24小时平均、白天和夜间)值(所有受试者综合)随年龄逐渐升高且差异显著。本研究提供了关于一个研究较少的人群(即不同种族背景的青少年和年轻成年人)ABP的初步规范性数据。研究还表明,在青少年和年轻成年人群体中,男性和非裔美国血统的受试者血压较高。