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美国开角型青光眼患病率和发病率模型。

Models of open-angle glaucoma prevalence and incidence in the United States.

作者信息

Quigley H A, Vitale S

机构信息

Dana Center for Preventive Opthalmology, Wilmer Institute, Johns Hopkins University school of Medicine, Bal;timore, Maryland 21287, USA.

出版信息

Invest Ophthalmol Vis Sci. 1997 Jan;38(1):83-91.

PMID:9008633
Abstract

PURPOSE

To estimate the prevalence and incidence of open-angle glaucoma among black and white persons in the United States and to characterize quantitatively their life experience with glaucoma using a life table approach to estimate disease duration.

METHODS

Review of published data on glaucoma combined with statistical models to estimate prevalence and incidence.

RESULTS

The association of open-angle glaucoma with age was examined separately for white and black persons. By the year 2000, the number of persons in the United States with primary open-angle glaucoma is estimated to be 2.47 million (1.84 million white and 619,000 black Americans). A model using derived incidence rates for open-angle glaucoma (OAG) and United States mortality data indicated that the average black American has OAG 27% longer than the average white American (16.3 years compared to 12.8 years).

CONCLUSIONS

Meta-analysis to obtain pooled prevalence estimates for glaucoma provides useful information on length of disease and age distribution of those affected. It may assist in estimating treatment effects and associated costs to derive data that effect health care decisions.

摘要

目的

评估美国黑人和白人中开角型青光眼的患病率和发病率,并采用寿命表法估计疾病持续时间,以定量描述他们患青光眼的生活经历。

方法

回顾已发表的青光眼数据,并结合统计模型来估计患病率和发病率。

结果

分别对白人和黑人中开角型青光眼与年龄的关联进行了研究。到2000年,估计美国原发性开角型青光眼患者人数为247万(184万白人及61.9万美国黑人)。一个使用开角型青光眼(OAG)推导发病率和美国死亡率数据的模型表明,美国黑人患OAG的平均时间比美国白人长27%(分别为16.3年和12.8年)。

结论

通过荟萃分析获得青光眼合并患病率估计值,可为疾病持续时间和受影响者的年龄分布提供有用信息。这可能有助于估计治疗效果和相关成本,以得出影响医疗保健决策的数据。

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