Khazaeli A A, Tatar M, Pletcher S D, Curtsinger J W
Department of Ecology, Evolution, and Behavior, University of Minnesota, USA.
J Gerontol A Biol Sci Med Sci. 1997 Jan;52(1):B48-52. doi: 10.1093/gerona/52a.1.b48.
Survival data were collected on a total of 28,000 Drosophila melanogaster adults in order to investigate mortality patterns and induced physiological responses after a mild thermal stress. A brief, nonlethal heat treatment extends adult life span at normal temperatures by an average of 2 days (64), compared to nontreated controls of the same genotypes. Life expectancy is extended as a demographic consequence of reduced age-specific mortality over a period of up to several weeks after the heat treatment. Heat treatment also increases tolerance to subsequent, more severe thermal stress. Observations on single-sex populations suggest that heat-induced longevity extension is independent of the suppression of reproductive activity.
为了研究果蝇在轻度热应激后的死亡率模式和诱导的生理反应，共收集了28000只黑腹果蝇成虫的存活数据。与相同基因型的未处理对照相比，短暂的非致死性热处理可使成虫在正常温度下的寿命平均延长2天（64）。热处理后长达数周的时间里，特定年龄死亡率降低，预期寿命因此延长。热处理还能提高对随后更严重热应激的耐受性。对单性别群体的观察表明，热诱导的寿命延长与生殖活动的抑制无关。
