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几内亚蒲桃(Willd)水溶性干提取物的体外抗菌活性筛选。

Screening of in vitro antibacterial activity from Syzygium Guineense (Willd) hydrosoluble dry extract.

作者信息

Tsakala T M, Penge O, John K

机构信息

Laboratoire de Pharmacie galénique, Faculté de Pharmacie, Kinshasa XI, Zaïre.

出版信息

Ann Pharm Fr. 1996;54(6):276-9.

PMID:9008903
Abstract

Diarrhoea is one of the most important causes of infant mortality in the world. As modern drugs are expensive or unavailable in developing countries, many people use traditional medicines in Africa for the treatment of several diseases. In our study, we investigated the antibacterial activity of Syzygium Guineense extract in order to assess its activity on some bacterial strains involved in diarrhoeal diseases and to justify its use. The aqueous dry extract was prepared by decoction followed by evaporating to dryness and tested according to dilution method. This extract showed an antibacterial activity against some bacterial strains: Salmonella E., Shigella D., Shigella F., E. Coli., Enterobacter A. It did not show any activity against Citrobacter F., Proteus M., Klebsiella P. Storage conditions (27 degrees C, glass flask) did not affect antibacterial properties of the extract.

摘要

腹泻是全球婴儿死亡的最重要原因之一。由于现代药物在发展中国家价格昂贵或难以获得,许多非洲人使用传统药物治疗多种疾病。在我们的研究中,我们调查了几内亚蒲桃提取物的抗菌活性,以评估其对一些引起腹泻疾病的细菌菌株的活性,并证明其使用的合理性。通过煎煮然后蒸发至干来制备水干提取物,并根据稀释法进行测试。该提取物对一些细菌菌株表现出抗菌活性:肠炎沙门氏菌、痢疾志贺氏菌、福氏志贺氏菌、大肠杆菌、产气肠杆菌。它对弗氏柠檬酸杆菌、摩氏变形杆菌、肺炎克雷伯菌没有表现出任何活性。储存条件(27摄氏度,玻璃瓶)不影响提取物的抗菌性能。

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