de Mendonça A, Ribeiro J A
Laboratory of Pharmacology, Gulbenkian Institute of Science, Oeiras, Portugal.
Life Sci. 1997;60(4-5):245-51. doi: 10.1016/s0024-3205(96)00544-9.
Adenosine is considered an important neuromodulator of the nervous system acting at pre-, post- and non-synaptic levels. In the present review we describe how adenosine modifies paired-pulse facilitation (PPF), posttetanic depression (PTD), long-term potentiation (LTP), long-term depression (LTD) and depotentiation at the hippocampus, and therefore how this nucleoside modulates synaptic plasticity.
腺苷被认为是一种重要的神经系统神经调质，作用于突触前、突触后和非突触水平。在本综述中，我们描述了腺苷如何改变海马体中的双脉冲易化（PPF）、强直后抑制（PTD）、长时程增强（LTP）、长时程抑制（LTD）和去增强作用，以及这种核苷如何调节突触可塑性。
