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[60天运动减少后近交系大鼠四肢骨骼对物理应激的适应性]

[Adaptation of the limb bones of inbred rats to physical stress following 60 days of hypokinesia].

作者信息

Nikitiuk B A, Kogan B I, Lominoga S I

出版信息

Arkh Anat Gistol Embriol. 1977 Apr;72(4):37-43.

PMID:901194
Abstract

Under study were the alterations in the extremity bones of inbred animals during 60-day-long hypokinesia. Variations of the correction of hypokinesia by physical loadings associated with the linear kind of animals were found and tested. Hypokinesia was shown to have inhibiting effects on the morphometrical parameters of flat (scapula, pelvic) and tubular (humeral, femoral, tibial) bones, the calcium and phosphorus content in blood serum being increased. Interlinear distinctions of the parameters studied under hypokinesia were revealed. The physical loading given against the background of restricted mobility normalizes the growth of bones, the level of calcium and phosphorus in the blood serum. The correction degree is dependent on the linear kind of animals speaking in favour of genotypical nature of adaptation of bones to physical loadings during hypokinesia.

摘要

对近交系动物在60天低动力状态下四肢骨骼的变化进行了研究。发现并测试了与动物体型相关的体力负荷对低动力状态的纠正变化。结果表明,低动力状态对扁骨(肩胛骨、骨盆)和管状骨(肱骨、股骨、胫骨)的形态测量参数有抑制作用,血清中钙和磷的含量增加。揭示了低动力状态下所研究参数的品系间差异。在活动受限的背景下进行体力负荷可使骨骼生长、血清中钙和磷的水平正常化。纠正程度取决于动物的体型,这支持了在低动力状态下骨骼对体力负荷适应的基因型性质。

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