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[低动力状态下过量磷摄入对大鼠磷钙代谢及骨组织的影响]

[Effect of excess phosphorus consumption on a phosphorus-calcium metabolism and bone tissue of rats under hypokinesia].

作者信息

Belakovskiĭ M S, Blazheevich N V, Spirichev V B, Sergeev I N, Spitsyna N E

出版信息

Kosm Biol Aviakosm Med. 1982 Sep-Oct;16(5):70-3.

PMID:7144101
Abstract

The exposure of rats fed with the diet containing Ca : P = 1 : 0.5 - 1 : 3 to hypokinesia produced hypocalcemia, osteoporosis and increased renal calcinosis. The reduced phosphorus consumption (Ca : P = 1 : 0.5 - 1 : 1) prevented these disorders in the intact animals and increased bone density in the hypokinetic rats. The excessive phosphorus consumption caused hypocalcemia, hyperphosphatemia and slight osteoporosis in both intact and hypokinetic rats, with the changes being more pronounced in those latter. It is concluded that the diet with Ca : P = = 1 : 0,5-1 : 1 is optimal for hypokinetic rats.

摘要

给大鼠喂食钙磷比为1:0.5至1:3的饮食,使其处于运动不足状态,会导致低钙血症、骨质疏松和肾钙质沉着增加。减少磷的摄入量(钙磷比为1:0.5至1:1)可预防正常动物出现这些病症,并增加运动不足大鼠的骨密度。摄入过量磷会导致正常大鼠和运动不足大鼠都出现低钙血症、高磷血症和轻度骨质疏松,且后者的变化更为明显。得出的结论是,钙磷比为1:0.5至1:1的饮食对运动不足的大鼠最为适宜。

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Kosm Biol Aviakosm Med. 1982 Sep-Oct;16(5):70-3.
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