Otto K A, Voight S, Piepenbrock S, Deegen E, Short C E
Abteilung Anästhesiologie II, Medizinische Hochschule Hannover, Germany.
Vet Surg. 1996 May-Jun;25(3):249-55. doi: 10.1111/j.1532-950x.1996.tb01409.x.
The effects of noxious surgical stimulation on the electroencephalogram (EEG) in 15 horses anesthetized with isoflurane were evaluated during orthopedic (group 1) and soft tissue (group 2) procedures. The quantitative EEG variables theta/delta ratio (T/D), alpha/delta ratio (A/D), beta/delta ratio (B/D), median power frequency (MED), and 80% spectral edge frequency (SEF 80) recorded during Surgeries at 1.7% end-tidal concentration of isoflurane (ET(iso)) were compared with values from five nonstimulated control horses anesthetized at 1,7% ET(iso). The EEG variables T/D, A/D, MED, and SEF 80 from surgically stimulated horses were significantly higher compared with controls. These differences in measured EEG variables were accompanied by a significantly lower relative power in the delta frequency band and a concomitant significantly higher alpha activity. Because the A/D ratio, MED, and SEF 80 in surgically stimulated horses were significantly higher than in nonstimulated control horses these measured EEG variables may provide a valuable tool for identification of nociceptive transmission in isoflurane anesthetized horses.
在15匹用异氟烷麻醉的马进行骨科手术（第1组）和软组织手术（第2组）期间，评估了有害手术刺激对脑电图（EEG）的影响。将在异氟烷呼气末浓度为1.7%（ET(iso)）的手术过程中记录的定量脑电图变量θ/δ比值（T/D）、α/δ比值（A/D）、β/δ比值（B/D）、中位功率频率（MED）和80%频谱边缘频率（SEF 80）与五匹在1.7% ET(iso)麻醉下的非刺激对照马的值进行比较。与对照组相比，手术刺激马的脑电图变量T/D、A/D、MED和SEF 80显著更高。测量的脑电图变量的这些差异伴随着δ频段相对功率显著降低以及α活动同时显著增加。由于手术刺激马的A/D比值、MED和SEF 80显著高于非刺激对照马，这些测量的脑电图变量可能为识别异氟烷麻醉马的伤害性传递提供有价值的工具。
