Orth M, Rasche K, Kollhosser P, Duchna H W, Bauer T T, Schultze-Werninghaus G
Abteilung für Pneumologie, Allergologie und Schlafmedizin, Berufsgenossenschaftlichen Kliniken Bergmannsheil, Universitätsklinik/Ruhr-Universität, Bochum, Deutschland.
Wien Med Wochenschr. 1996;146(13-14):357-8.
Although the prevalence of obstructive sleep apnea syndrome (OSAS) is about 4% in men and 2% in women, women are underrepresented in clinical routine. The aim of this study was to determine whether differences in clinical features of OSAS may in part explain the bias observed. 224 men and 24 women with polysomnographically confirmed OSAS filled in a symptom-focussed multiple-choice questionnaire. Polysomnographical results were comparable in both groups. With regard to snoring, daytime sleepiness and tendency of falling asleep there were no differences between both groups. Women more frequently complained about difficulties of initiating and maintaining sleep and about apneas. Further investigations have to concentrate on the pathomechanisms of OSAS in women which may in part explain the gender differences in sleep apnea associated symptoms.
尽管阻塞性睡眠呼吸暂停综合征（OSAS）在男性中的患病率约为4%，在女性中为2%，但在临床常规诊疗中女性患者的比例较低。本研究的目的是确定OSAS临床特征的差异是否能部分解释所观察到的偏差。224名经多导睡眠图确诊为OSAS的男性和24名女性填写了一份以症状为重点的多项选择题问卷。两组的多导睡眠图结果具有可比性。在打鼾、日间嗜睡和入睡倾向方面，两组之间没有差异。女性更频繁地抱怨入睡和维持睡眠困难以及呼吸暂停。进一步的研究必须集中在女性OSAS的发病机制上，这可能部分解释睡眠呼吸暂停相关症状的性别差异。
