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接受体外受精的多囊卵巢患者的治疗。

Treatment of polycystic ovary patients undergoing IVF.

作者信息

Barri P N, Coroleu B, Martinez F, Traver J M, Veiga A, Calderon G

机构信息

Department of Obstetrics and Gynecology, Institut Universitari Dexeus, Barcelona, Spain.

出版信息

J Assist Reprod Genet. 1997 Jan;14(1):10-2. doi: 10.1007/BF02765743.

DOI:10.1007/BF02765743
PMID:9013302
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3454708/
Abstract

We believe that PCO patients can achieve good results in IVF cycles, provided that stimulation protocols appropriate to their hormonal profiles are used. The dose of gonadotropin used seems to be more important than the type of gonadotropin. If there is a risk of ovarian hyperstimulation, it is useful to employ one of the strategies recommended to prevent development of genuine OHS, which may endanger the patient’s health.

摘要

我们认为，多囊卵巢综合征（PCO）患者在体外受精（IVF）周期中可以取得良好的效果，前提是使用适合其激素水平的促排卵方案。所用促性腺激素的剂量似乎比促性腺激素的类型更为重要。如果存在卵巢过度刺激的风险，采用推荐的预防真正卵巢过度刺激综合征（OHS）发生的策略之一是有用的，因为真正的OHS可能危及患者健康。

相似文献

1
Treatment of polycystic ovary patients undergoing IVF.接受体外受精的多囊卵巢患者的治疗。
J Assist Reprod Genet. 1997 Jan;14(1):10-2. doi: 10.1007/BF02765743.
2
The treatment of patients with polycystic ovaries undergoing IVF.接受体外受精的多囊卵巢患者的治疗。
J Assist Reprod Genet. 1997 Jan;14(1):12-4. doi: 10.1007/BF02765744.
3
Clinical utility of adjuvant growth hormone in the treatment of patients with polycystic ovaries undergoing in vitro fertilization.辅助生长激素在接受体外受精的多囊卵巢患者治疗中的临床应用
J Assist Reprod Genet. 1997 Jan;14(1):4-7. doi: 10.1007/BF02765741.
4
In vitro fertilization treatment in patients with polycystic ovaries.多囊卵巢患者的体外受精治疗
J Assist Reprod Genet. 1997 Jan;14(1):7-10. doi: 10.1007/BF02765742.
5
The significance of high follicular-phase luteinizing hormone levels in the treatment of women with polycystic ovarian syndrome by in vitro fertilization.卵泡期促黄体生成素水平升高在多囊卵巢综合征女性体外受精治疗中的意义
J Assist Reprod Genet. 1997 Jan;14(1):1-4. doi: 10.1007/BF02765740.
6
The use of gonadotropin-releasing hormone (GnRH) agonist to induce oocyte maturation after cotreatment with GnRH antagonist in high-risk patients undergoing in vitro fertilization prevents the risk of ovarian hyperstimulation syndrome: a prospective randomized controlled study.在接受体外受精的高危患者中，促性腺激素释放激素（GnRH）激动剂与GnRH拮抗剂联合治疗后用于诱导卵母细胞成熟可预防卵巢过度刺激综合征的风险：一项前瞻性随机对照研究。
Fertil Steril. 2008 Jan;89(1):84-91. doi: 10.1016/j.fertnstert.2007.02.002. Epub 2007 Apr 26.
7
Miscarriage rates following in-vitro fertilization are increased in women with polycystic ovaries and reduced by pituitary desensitization with buserelin.多囊卵巢女性体外受精后的流产率会升高，而使用布舍瑞林进行垂体脱敏可降低流产率。
Hum Reprod. 1993 Jun;8(6):959-64. doi: 10.1093/oxfordjournals.humrep.a138174.
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Comparison between flare up and down regulation effects of luteinizing hormone-releasing hormone agonists in an in vitro fertilization program.体外受精程序中促黄体生成素释放激素激动剂的 flare up 与下调作用之间的比较。 （注：“flare up”在医学领域可能有特定含义，具体需结合上下文准确理解，这里直接保留英文表述是因为不太明确其在该语境下的精准中文术语。）
Fertil Steril. 1988 Sep;50(3):471-5. doi: 10.1016/s0015-0282(16)60135-8.
9
In-vitro maturation of oocytes vs in-vitro fertilization with a gonadotropin-releasing hormone antagonist for women with polycystic ovarian syndrome: can superiority be defined?多囊卵巢综合征女性卵母细胞体外成熟与促性腺激素释放激素拮抗剂体外受精的比较：能否确定优势？
Eur J Obstet Gynecol Reprod Biol. 2014 Aug;179:46-50. doi: 10.1016/j.ejogrb.2014.05.013. Epub 2014 Jun 2.
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Stimulation with human menopausal gonadotropin versus follicle-stimulating hormone after pituitary suppression in polycystic ovarian syndrome.多囊卵巢综合征垂体抑制后，人绝经期促性腺激素与促卵泡激素刺激的比较
Fertil Steril. 1990 May;53(5):798-803. doi: 10.1016/s0015-0282(16)53512-2.

本文引用的文献

1
Adjuvant growth hormone for induction of ovulation with gonadotrophin-releasing hormone agonist and gonadotrophins in polycystic ovary syndrome: a randomized, double-blind, placebo controlled trial.多囊卵巢综合征中辅助使用生长激素联合促性腺激素释放激素激动剂和促性腺激素诱导排卵：一项随机、双盲、安慰剂对照试验
Hum Reprod. 1995 Oct;10(10):2550-3. doi: 10.1093/oxfordjournals.humrep.a135743.
2
The prognostic value of basal luteinizing hormone:follicle-stimulating hormone ratio in the treatment of patients with polycystic ovarian syndrome by assisted reproduction techniques.基础促黄体生成素与促卵泡生成素比值在多囊卵巢综合征患者辅助生殖技术治疗中的预后价值
Hum Reprod. 1995 Oct;10(10):2545-9. doi: 10.1093/oxfordjournals.humrep.a135742.
3
Polycystic ovary syndrome: pathophysiology and outcome with in vitro fertilization.多囊卵巢综合征：病理生理学与体外受精结局
Fertil Steril. 1996 Jan;65(1):1-10. doi: 10.1016/s0015-0282(16)58017-0.
4
Clinical evidence for a detrimental effect on uterine receptivity of high serum oestradiol concentrations in high and normal responder patients.高反应者和正常反应者中高血清雌二醇浓度对子宫容受性产生有害影响的临床证据。
Hum Reprod. 1995 Sep;10(9):2432-7. doi: 10.1093/oxfordjournals.humrep.a136313.
5
Cumulative birth rates following cryopreservation of all embryos in stimulated in vitro fertilization (IVF) cycles.在体外受精（IVF）促排卵周期中对所有胚胎进行冷冻保存后的累积出生率。
J Assist Reprod Genet. 1995 Mar;12(3):191-4. doi: 10.1007/BF02211797.
6
Oocyte donation in low responders to conventional ovarian stimulation for in vitro fertilization.对于体外受精常规卵巢刺激反应低下者的卵母细胞捐赠
Fertil Steril. 1993 Jun;59(6):1208-15. doi: 10.1016/s0015-0282(16)55978-0.
7
Gonadotropin-releasing hormone agonist reduces the miscarriage rate for pregnancies achieved in women with polycystic ovarian syndrome.促性腺激素释放激素激动剂可降低多囊卵巢综合征女性妊娠后的流产率。
Fertil Steril. 1993 Mar;59(3):527-31. doi: 10.1016/s0015-0282(16)55794-x.
8
The use of intravenous albumin in patients at high risk for severe ovarian hyperstimulation syndrome.
Hum Reprod. 1993 Jul;8(7):1015-20. doi: 10.1093/oxfordjournals.humrep.a138185.
9
Assisted reproduction techniques in polycystic ovarian syndrome.多囊卵巢综合征中的辅助生殖技术。
Ann N Y Acad Sci. 1993 May 28;687:280-7. doi: 10.1111/j.1749-6632.1993.tb43877.x.
10
Hypersecretion of luteinising hormone: a significant cause of infertility and miscarriage.
Br J Obstet Gynaecol. 1993 Dec;100(12):1082-9. doi: 10.1111/j.1471-0528.1993.tb15170.x.